BDBM50021376 CHEMBL3289569

SMILES CN(CCCC(c1ccccc1)c1ccccc1)C(CCN)C(=O)NCc1ccccc1

InChI Key InChIKey=ACUKXRUOCHOLBD-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50021376   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021376(CHEMBL3289569)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021376(CHEMBL3289569)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021376(CHEMBL3289569)
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021376(CHEMBL3289569)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021376(CHEMBL3289569)
Affinity DataKi:  3.09E+4nMAssay Description:Displacement of NO711 from mouse GAT1 expressed in HEK293 cells by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed