BDBM50021186 4-Amino-3-hydroxy-butyric acid::CHEMBL296263::S(+)-4-amino-3-hydroxybutanoic acid

SMILES NC[C@@H](O)CC(O)=O

InChI Key InChIKey=YQGDEPYYFWUPGO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021186   

LigandPNGBDBM50021186(CHEMBL296263 | S(+)-4-amino-3-hydroxybutanoic acid...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of [3H]GABA binding to Gamma-aminobutyric acid receptor of rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50021186(CHEMBL296263 | S(+)-4-amino-3-hydroxybutanoic acid...)
Affinity DataEC50:  4.48E+4nMAssay Description:Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50021186(CHEMBL296263 | S(+)-4-amino-3-hydroxybutanoic acid...)
Affinity DataIC50: 2.90E+4nMAssay Description:In vitro inhibition of GABA uptake in rat brain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed