BDBM50020947 CHEMBL3287310

SMILES CS(=O)(=O)Cc1cccc(c1)Nc2nccc(n2)Oc3ccc(cc3F)NC(=O)C4(CC4)C(=O)Nc5ccc(cc5)F

InChI Key InChIKey=SEERCQIVLBZZJL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020947   

TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50020947(CHEMBL3287310)
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50020947(CHEMBL3287310)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)