BDBM50020919 CHEMBL3287282

SMILES OC(=O)c1cccc(n1)-c1ccc2CCC\C(=N/Nc3nc4ccccc4s3)c2c1

InChI Key InChIKey=ZGERKAMDOWOUTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020919   

TargetBcl-2-like protein 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50020919(CHEMBL3287282)
Affinity DataIC50: 20nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50020919(CHEMBL3287282)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at Bcl-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50020919(CHEMBL3287282)
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) measured after 1 hr incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed