BDBM50020702 3-(2-Dipropylamino-ethyl)-1H-indol-5-ol::3-(2-Dipropylamino-ethyl)-1H-indol-5-ol(DiPS)::CHEMBL141706

SMILES CCCN(CCC)CCc1c[nH]c2ccc(O)cc12

InChI Key InChIKey=CWMOGUBWVJQDSL-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50020702   

Target5-hydroxytryptamine receptor 1D(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020702(CHEMBL141706 | 3-(2-Dipropylamino-ethyl)-1H-indol-...)
Affinity DataIC50: 820nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor alpha expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020702(CHEMBL141706 | 3-(2-Dipropylamino-ethyl)-1H-indol-...)
Affinity DataIC50: 820nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50020702(CHEMBL141706 | 3-(2-Dipropylamino-ethyl)-1H-indol-...)
Affinity DataKi:  1nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]- 1-(4-bromo-2,5-dimethoxy-phenyl)-2-aminopropane (D) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50020702(CHEMBL141706 | 3-(2-Dipropylamino-ethyl)-1H-indol-...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in rat hippocampal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50020702(CHEMBL141706 | 3-(2-Dipropylamino-ethyl)-1H-indol-...)
Affinity DataKi:  450nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]- ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50020702(CHEMBL141706 | 3-(2-Dipropylamino-ethyl)-1H-indol-...)
Affinity DataKi:  4.30E+3nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed