BDBM50020686 4-(2-Amino-ethyl)-7-hydroxy-1,3-dihydro-indol-2-one::CHEMBL278188

SMILES NCCc1ccc(O)c2NC(=O)Cc12

InChI Key InChIKey=ZAHNXSYMXOCYFR-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020686   

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50020686(CHEMBL278188 | 4-(2-Amino-ethyl)-7-hydroxy-1,3-dih...)
Affinity DataEC50:  4.65E+3nMAssay Description:Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes. Partial agonist...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50020686(CHEMBL278188 | 4-(2-Amino-ethyl)-7-hydroxy-1,3-dih...)
Affinity DataIC50: 4.85E+3nMAssay Description:Displacement of [3H]spiroperidol from homogenized bovine pituitary Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50020686(CHEMBL278188 | 4-(2-Amino-ethyl)-7-hydroxy-1,3-dih...)
Affinity DataEC50:  116nMAssay Description:Tested in vitro for dopamine agonist activity in rabbit ear artery after at a dose of 3 ug/kgMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50020686(CHEMBL278188 | 4-(2-Amino-ethyl)-7-hydroxy-1,3-dih...)
Affinity DataEC50:  116nMAssay Description:Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed