BDBM50020220 3-Dipropylamino-chroman-8-ol::CHEMBL38428

SMILES CCCN(CCC)C1COc2c(O)cccc2C1

InChI Key InChIKey=PXSSMALRVSYAFM-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50020220   

TargetD(2) dopamine receptor(Rat)
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020220(CHEMBL38428 | 3-Dipropylamino-chroman-8-ol)
Affinity DataIC50: 4nMAssay Description:Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020220(CHEMBL38428 | 3-Dipropylamino-chroman-8-ol)
Affinity DataIC50: 10nMAssay Description:In vitro affinity to dopamine receptor using [3H]HPD as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2019
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020220(CHEMBL38428 | 3-Dipropylamino-chroman-8-ol)
Affinity DataIC50: 0.320nMAssay Description:In vitro affinity to dopamine receptor using [3H]NPAD as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50020220(CHEMBL38428 | 3-Dipropylamino-chroman-8-ol)
Affinity DataKi:  128nMAssay Description:In vitro ability to inhibit [3H]raclopride binding to cloned human D2A receptors expressed in mouse fibroblast (LtK-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50020220(CHEMBL38428 | 3-Dipropylamino-chroman-8-ol)
Affinity DataKi: >3.00E+3nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed