BDBM50019949 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butan-1-one::CHEMBL54206

SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccccc1

InChI Key InChIKey=FEFFZKPQSVTBAY-UHFFFAOYSA-N

Data  2 KI  4 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50019949   

TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 3.22E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKd:  8.5nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKd:  8.5nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-acetyltransferase Eis(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 850nMAssay Description:Inhibition of Mycobacterium tuberculosis Eis assessed as Eis-mediated kanamycin acetylation preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKi:  7.60nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKi:  7.60nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed