BDBM50019874 CHEMBL3287169

SMILES CC(=O)N1CCc2cc(ccc12)-c1cccnc1

InChI Key InChIKey=ABLRUBDAIDDHIM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50019874   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50019874(CHEMBL3287169)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50019874(CHEMBL3287169)
Affinity DataIC50: 60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50019874(CHEMBL3287169)
Affinity DataIC50: 5nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50019874(CHEMBL3287169)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50019874(CHEMBL3287169)
Affinity DataIC50: 60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblasts using deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50019874(CHEMBL3287169)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblasts using deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed