BDBM50019417 CHEMBL3290101

SMILES COc1cccc(OC)c1-c1cc(nn1-c1cccc2ccccc12)C(=O)NC1(CCCCC1)C(O)=O

InChI Key InChIKey=BTEJVDICTLPRLK-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019417   

TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50019417(CHEMBL3290101)
Affinity DataEC50:  18nMAssay Description:Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50019417(CHEMBL3290101)
Affinity DataKi:  116nMAssay Description:Displacement of [125I]NT at rat NTS2 overexpressed in CHOK1 cells after 30 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Rat)
Rti International

Curated by ChEMBL
LigandPNGBDBM50019417(CHEMBL3290101)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [I125]neurotensin from rat NTS1 overexpressed in CHO-k1 cells by competitive binding AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed