BDBM50019388 6-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-hexanoic acid::6-amino-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)hexanoic acid::CHEMBL418165

SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)NC(CCCCN)C(O)=O

InChI Key InChIKey=XERJQLWAFDLUGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019388   

TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50019388(CHEMBL418165 | 6-amino-2-(4-(((2,4-diaminopteridin...)
Affinity DataIC50: 65nMAssay Description:Compound was tested for its ability to inhibit purified dihydrofolate reductase(DHFR) from L1210/R81 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed