BDBM50017451 1-(2-Propyl-phenyl)-piperazine::CHEMBL9870

SMILES CCCc1ccccc1N1CCNCC1

InChI Key InChIKey=FHIDPEUFJOUCRS-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50017451   

Target5-hydroxytryptamine receptor 1B(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide

Curated by ChEMBL
LigandPNGBDBM50017451(CHEMBL9870 | 1-(2-Propyl-phenyl)-piperazine)
Affinity DataKi:  16nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide

Curated by ChEMBL
LigandPNGBDBM50017451(CHEMBL9870 | 1-(2-Propyl-phenyl)-piperazine)
Affinity DataKi:  19nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide

Curated by ChEMBL
LigandPNGBDBM50017451(CHEMBL9870 | 1-(2-Propyl-phenyl)-piperazine)
Affinity DataKi:  35nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide

Curated by ChEMBL
LigandPNGBDBM50017451(CHEMBL9870 | 1-(2-Propyl-phenyl)-piperazine)
Affinity DataKi:  117nMAssay Description:Binding affinity against rat Alpha-1 adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide

Curated by ChEMBL
LigandPNGBDBM50017451(CHEMBL9870 | 1-(2-Propyl-phenyl)-piperazine)
Affinity DataKi:  232nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 2 receptor by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide

Curated by ChEMBL
LigandPNGBDBM50017451(CHEMBL9870 | 1-(2-Propyl-phenyl)-piperazine)
Affinity DataKi:  379nMAssay Description:Binding affinity against rat Dopamine receptor D2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide

Curated by ChEMBL
LigandPNGBDBM50017451(CHEMBL9870 | 1-(2-Propyl-phenyl)-piperazine)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at rat Dopamine receptor D1 by [3H]SCH-23390 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed