BDBM50017214 (-)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide::(SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide(U 50488)::CHEMBL60547

SMILES CN([C@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=VQLPLYSROCPWFF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017214   

TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  81nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  167nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor kappa 1 using [3H]BREM in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  250nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H]DTG in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
National Institute of Digestive

Curated by ChEMBL
LigandPNGBDBM50017214((SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrroli...)
Affinity DataKi:  3.73E+3nMAssay Description:Compound was evaluated for binding affinity towards Dopamine receptor D2 using [3H]SULP in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed