BDBM50017108 4-(3,4-Dimethoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid ethyl ester::CHEMBL36182

SMILES CCOC(=O)C1C(CNC1=O)c1ccc(OC)c(OC)c1

InChI Key InChIKey=PQCRPXRLLDACRS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017108   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017108(CHEMBL36182 | 4-(3,4-Dimethoxy-phenyl)-2-oxo-pyrro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP for cGMP-PDE;Compound is insignificant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017108(CHEMBL36182 | 4-(3,4-Dimethoxy-phenyl)-2-oxo-pyrro...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017108(CHEMBL36182 | 4-(3,4-Dimethoxy-phenyl)-2-oxo-pyrro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against cAMP phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP in the presence of calcium (10 uM) and ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed