BDBM50017092 4-(3-Isobutoxy-4-methoxy-phenyl)-pyrrolidin-2-one::CHEMBL416770

SMILES COc1ccc(cc1OCC(C)C)C1CNC(=O)C1

InChI Key InChIKey=AGQGSLHQIUKIEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017092   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017092(CHEMBL416770 | 4-(3-Isobutoxy-4-methoxy-phenyl)-py...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP for cGMP-PDE;Compound is insignificant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017092(CHEMBL416770 | 4-(3-Isobutoxy-4-methoxy-phenyl)-py...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017092(CHEMBL416770 | 4-(3-Isobutoxy-4-methoxy-phenyl)-py...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP in the presence of calcium (10 uM) and calmodu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed