BDBM50016959 4-Methyl-1-[4-(4-thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione; hydrochloride::CHEMBL537924

SMILES CC1CC(=O)N(CCCCN2CCN(CC2)c2nccc3sccc23)C(=O)C1

InChI Key InChIKey=LKUJZLFUMLHSCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016959   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016959(CHEMBL537924 | 4-Methyl-1-[4-(4-thieno[3,2-c]pyrid...)
Affinity DataIC50: 4.20nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 2 receptors of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016959(CHEMBL537924 | 4-Methyl-1-[4-(4-thieno[3,2-c]pyrid...)
Affinity DataIC50: 8.80nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016959(CHEMBL537924 | 4-Methyl-1-[4-(4-thieno[3,2-c]pyrid...)
Affinity DataIC50: 663nMAssay Description:Ability to bind at dopamine receptor D2 of rat corpus striatum by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50016959(CHEMBL537924 | 4-Methyl-1-[4-(4-thieno[3,2-c]pyrid...)
Affinity DataIC50: 1.30nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed