BDBM50016909 CHEMBL140417::Methyl-[2-(naphthalen-1-yloxy)-ethyl]-propyl-amine

SMILES CCCN(C)CCOc1cccc2ccccc12

InChI Key InChIKey=NNOQKMUYNWQAJH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50016909   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016909(CHEMBL140417 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor of rat hippocampal tissue using [3H]OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016909(CHEMBL140417 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Affinity DataKi:  103nMAssay Description:Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Medical College of Virginia/Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016909(CHEMBL140417 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Affinity DataKi:  750nMAssay Description:Agonist activity to the human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016909(CHEMBL140417 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat striatal membrane homogenate using [3H]5-HT as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016909(CHEMBL140417 | Methyl-[2-(naphthalen-1-yloxy)-ethy...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity against beta adrenergic receptor of rat frontal cortex homogenate using (1.0 nM) [3H]- dihydroalprenololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed