BDBM50016166 CHEMBL3261517
SMILES COc1ccc(-c2nc(sc2C(N)=O)-c2ccnc(N)n2)c(Cl)c1
InChI Key InChIKey=VCUXVXLUOHDHKK-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50016166
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 862nMAssay Description:Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK1/Cyclin-B (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK4/Cyclin-D1 (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 729nMAssay Description:Inhibition of CDK9/Cyclin-T1 (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 545nMAssay Description:Inhibition of CK1alpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Inhibition of CK1delta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Pim1 (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair