BDBM50015857 3-Acetoxymethyl-5,5,8-trioxo-7-phenylacetoxy-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester::CHEMBL421718

SMILES CC(=O)OCC1=C(N2[C@@H]([C@@H](OC(=O)Cc3ccccc3)C2=O)S(=O)(=O)C1)C(=O)OC(C)(C)C

InChI Key InChIKey=SSACDUNHDNYWAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50015857   

TargetChymotrypsinogen A(Bovine)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(CHEMBL421718 | 3-Acetoxymethyl-5,5,8-trioxo-7-phen...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of alpha-chymotrypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(CHEMBL421718 | 3-Acetoxymethyl-5,5,8-trioxo-7-phen...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(CHEMBL421718 | 3-Acetoxymethyl-5,5,8-trioxo-7-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 1/2A(Pig)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(CHEMBL421718 | 3-Acetoxymethyl-5,5,8-trioxo-7-phen...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of Porcine pancreatic elastase (PPE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed