BDBM50015547 CHEMBL3265335

SMILES [H][C@]12COCC[C@]1([H])[C@]1(COC(N)=N1)c1cc(ccc1O2)-c1cncc(Cl)c1

InChI Key InChIKey=BGRWOLNAPSRJIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015547   

TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50: 130nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed