BDBM50015541 CHEMBL3265331

SMILES [H][C@@]12COCC[C@@]1([H])[C@]1(COC(N)=N1)c1cc(ccc1O2)-c1cccnc1F

InChI Key InChIKey=VXNSVIMZLURETA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015541   

TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015541(CHEMBL3265331)
Affinity DataIC50: 150nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015541(CHEMBL3265331)
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed