BDBM50015432 6-Methyl-2-methylsulfanyl-4-(3-nitro-phenyl)-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL39925

SMILES CCOC(=O)C1C(N=C(SC)N=C1C)c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=KZFSUAKBPHDHBT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015432   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50015432(CHEMBL39925 | 6-Methyl-2-methylsulfanyl-4-(3-nitro...)
Affinity DataKd:  23nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50015432(CHEMBL39925 | 6-Methyl-2-methylsulfanyl-4-(3-nitro...)
Affinity DataIC50: 130nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed