BDBM50015178 (E)-N-hydroxy-N-methyl-3-(naphthalen-2-yl)acrylamide::CHEMBL63882::N-Hydroxy-N-methyl-3-naphthalen-2-yl-acrylamide

SMILES CN(O)C(=O)\C=C\c1ccc2ccccc2c1

InChI Key InChIKey=CORKVTFWNIPMDF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50015178   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015178(CHEMBL63882 | (E)-N-hydroxy-N-methyl-3-(naphthalen...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015178(CHEMBL63882 | (E)-N-hydroxy-N-methyl-3-(naphthalen...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015178(CHEMBL63882 | (E)-N-hydroxy-N-methyl-3-(naphthalen...)
Affinity DataIC50: 100nMAssay Description:Compound was tested for its in vitro inhibitory activity against RBL-1 5-LO (time dependent)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015178(CHEMBL63882 | (E)-N-hydroxy-N-methyl-3-(naphthalen...)
Affinity DataIC50: 100nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed