BDBM50015149 CHEMBL156887::N-Hydroxy-4-naphthalen-1-yl-benzamide::N-hydroxy-4-(naphthalen-1-yl)benzamide

SMILES ONC(=O)c1ccc(cc1)-c1cccc2ccccc12

InChI Key InChIKey=PKQVYJOPUCLLCD-UHFFFAOYSA-N

Data  2 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50015149   

TargetHistone deacetylase 8(Human)
Ithaca College

Curated by ChEMBL
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human HDAC8 by [3H]acetyl histone peptide assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Ithaca College

Curated by ChEMBL
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC1 by [3H]acetyl histone peptide assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Ithaca College

Curated by ChEMBL
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human HDAC6 by [3H]acetyl histone peptide assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 180nMAssay Description:Compound was tested for its in vitro inhibitory activity against RBL-1 5-LO (time dependent)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 182nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1974(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
Foundation For Research& Technology-Hellas

Curated by ChEMBL
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 4.33E+4nMAssay Description:Inhibition of recombinant Bacillus cereus BC1974 expressed in Escherichia coli using GlcNAc5 as substrate measured after 5 mins by fluorescamine base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1960(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
Foundation For Research& Technology-Hellas

Curated by ChEMBL
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of recombinant Bacillus cereus BC1960 expressed in Escherichia coli using GlcNAc5 as substrate measured after 10 mins by fluorescamine bas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1974(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
Foundation For Research& Technology-Hellas

Curated by ChEMBL
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataKi:  8.70E+3nMAssay Description:Competitive inhibition of recombinant Bacillus cereus BC1974 expressed in Escherichia coli using varying levels of GlcNAc5 as substrate measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1960(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
Foundation For Research& Technology-Hellas

Curated by ChEMBL
LigandPNGBDBM50015149(N-hydroxy-4-(naphthalen-1-yl)benzamide | CHEMBL156...)
Affinity DataKi:  6.60E+4nMAssay Description:Competitive inhibition of recombinant Bacillus cereus BC1960 expressed in Escherichia coli using varying levels of GlcNAc5 as substrate measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed