BDBM50014480 (S)-2-(4-(((4-oxo-3,4-dihydroquinazolin-6-yl)methyl)(prop-2-ynyl)amino)benzamido)pentanedioic acid::2-{4-[(4-Oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL103059
SMILES OC(=O)CC[C@H](NC(=O)c1ccc(cc1)N(CC#C)Cc1ccc2nc[nH]c(=O)c2c1)C(O)=O
InChI Key InChIKey=AOGOUTMDEVCZHA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50014480
Affinity DataIC50: 160nMAssay Description:Binding affinity against Thymidylate synthase was measured in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Concentration required to inhibit 50% activity of Thymidylate synthase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity against Thymidylate synthase was measured in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition of thymidylate synthase, partially purified from L1210 mouse leukemia cells overexpressing TSMore data for this Ligand-Target Pair
Affinity DataKi: 2.25E+3nMAssay Description:Inhibitory activity against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair