BDBM50013685 9-Isopropyl-9H-adenine::9-Isopropyl-9H-purin-6-ylamine::CHEMBL67199

SMILES CC(C)n1cnc2c(N)ncnc12

InChI Key InChIKey=BCMZIPWCRGOWEV-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50013685   

TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013685(CHEMBL67199 | 9-Isopropyl-9H-adenine | 9-Isopropyl...)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50013685(CHEMBL67199 | 9-Isopropyl-9H-adenine | 9-Isopropyl...)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50013685(CHEMBL67199 | 9-Isopropyl-9H-adenine | 9-Isopropyl...)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013685(CHEMBL67199 | 9-Isopropyl-9H-adenine | 9-Isopropyl...)
Affinity DataKi:  1.03E+4nMAssay Description:Binding affinity (Ki) against human phosphatidylinositol 4-kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50013685(CHEMBL67199 | 9-Isopropyl-9H-adenine | 9-Isopropyl...)
Affinity DataKi:  1.60E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50013685(CHEMBL67199 | 9-Isopropyl-9H-adenine | 9-Isopropyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed