BDBM50013534 2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]-phenoxymethyl}-quinoline::2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]-phenoxymethyl}-quinoline (RG 7152)::CHEMBL418551

SMILES C(COc1cccc(OCc2ccc3ccccc3n2)c1)Cc1nnn[nH]1

InChI Key InChIKey=XDPLTERFGJAMRU-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50013534   

TargetCysteinyl leukotriene receptor 1/2(Human)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013534(CHEMBL418551 | 2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]...)
Affinity DataIC50: 79nMAssay Description:Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013534(CHEMBL418551 | 2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]...)
Affinity DataKi:  42nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]LTD4 (0.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013534(CHEMBL418551 | 2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]...)
Affinity DataKi:  42nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]LTD4 (0.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013534(CHEMBL418551 | 2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]...)
Affinity DataKi:  42nMAssay Description:In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed