BDBM50013526 2-(3-Butoxy-phenoxymethyl)-quinoline::CHEMBL18775

SMILES CCCCOc1cccc(OCc2ccc3ccccc3n2)c1

InChI Key InChIKey=UBDSCBZDTZHXHG-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013526   

TargetCysteinyl leukotriene receptor 1/2(Human)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013526(CHEMBL18775 | 2-(3-Butoxy-phenoxymethyl)-quinoline)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50013526(CHEMBL18775 | 2-(3-Butoxy-phenoxymethyl)-quinoline)
Affinity DataEC50:  500nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013526(CHEMBL18775 | 2-(3-Butoxy-phenoxymethyl)-quinoline)
Affinity DataKi:  3.80E+3nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]LTD4 (0.2 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed