BDBM50013510 CHEMBL3263773

SMILES COc1ccccc1-c1cc(Nc2cccc(CS(N)(=O)=O)c2)ncn1

InChI Key InChIKey=GGQCIOOSELPMBB-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50013510   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Vichem Chemie

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using MBP peptide substrate after 1 hr by FRET-based LANCE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) using RPPTLSPIPHIPR peptide as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 4.96E+3nMAssay Description:Inhibition of CDK5/p35NCK (unknown origin) using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Vichem Chemie

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 44nMAssay Description:Inhibition of full length human recombinant His-tagged CDK9/cyclin T expressed in baculovirus expression system using ULight MBP peptide substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human CDK9 using ULight MBP peptide as substrate incubated for 1 hr in presence of ATP by TR-FRET based LANCE assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubate...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of CDK1/cyclin B1 (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubate...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubated...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 9.24E+3nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubate...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 6(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK6 (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 7(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK7 (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed