BDBM50012981 5-(1H-Indol-3-yl)-6-piperidin-1-yl-bicyclo[2.2.2]octan-2-one::CHEMBL338310

SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCCC1

InChI Key InChIKey=SQIRNABIBUHYJX-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50012981   

Target5-hydroxytryptamine receptor 1A(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataKi:  6.10E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012981(CHEMBL338310 | 5-(1H-Indol-3-yl)-6-piperidin-1-yl-...)
Affinity DataKi:  6.10E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed