BDBM50012887 CHEMBL65430::N-Hydroxy-2-(4-isobutyl-phenyl)-N-methyl-propionamide::N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide

SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O

InChI Key InChIKey=LIUJRXOTKOJLOG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50012887   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012887(N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 5-lipoxygenase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012887(N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide...)
Affinity DataIC50: 288nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012887(N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide...)
Affinity DataIC50: 980nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012887(N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012887(N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012887(N-hydroxy-2-(4-isobutylphenyl)-N-methylpropanamide...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed