BDBM50011227 2-Benzyl-N-{1-[1-cyclohexylmethyl-2-(3-ethyl-2-oxo-oxazolidin-5-yl)-2-hydroxy-ethylcarbamoyl]-2-thiophen-2-yl-ethyl}-4-morpholin-4-yl-4-oxo-butyramide::CHEMBL341975

SMILES CCN1C[C@H](OC1=O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cccs1)NC(=O)[C@@H](CC(=O)N1CCOCC1)Cc1ccccc1

InChI Key InChIKey=HBNQGHTYKIVMHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011227   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011227(CHEMBL341975 | 2-Benzyl-N-{1-[1-cyclohexylmethyl-2...)
Affinity DataIC50: 1.5nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011227(CHEMBL341975 | 2-Benzyl-N-{1-[1-cyclohexylmethyl-2...)
Affinity DataIC50: 43nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011227(CHEMBL341975 | 2-Benzyl-N-{1-[1-cyclohexylmethyl-2...)
Affinity DataIC50: 43nMpH: 7.4Assay Description:Compound was evaluated for the inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed