BDBM50011187 CHEMBL3260323::US10112928, Compound I-30

SMILES Cc1cccc(Nc2cc(N[C@@H]3CCCC[C@@H]3N)ccc2C(N)=O)n1

InChI Key InChIKey=GTXJLJRDPSWJNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011187   

TargetTyrosine-protein kinase SYK(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50011187(CHEMBL3260323 | US10112928, Compound I-30)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant SYK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50011187(CHEMBL3260323 | US10112928, Compound I-30)
Affinity DataIC50: 41.8nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In DepthDetails
US Patent