BDBM50010806 CHEMBL78306::N,N'-Bis-(5,6,7,8-tetrahydro-naphthalen-1-yl)-guanidine

SMILES NC(Nc1cccc2CCCCc12)=Nc1cccc2CCCCc12

InChI Key InChIKey=KJOYRIVJBJOCQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010806   

TargetSigma non-opioid intracellular receptor 1(Human)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010806(CHEMBL78306 | N,N'-Bis-(5,6,7,8-tetrahydro-naphtha...)
Affinity DataIC50: 59nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010806(CHEMBL78306 | N,N'-Bis-(5,6,7,8-tetrahydro-naphtha...)
Affinity DataIC50: 59nMAssay Description:In vitro inhibitory activity against [3H]-DTG in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed