BDBM50009832 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL269550
SMILES CCOC(=O)C1CN(Cc2ccccc2)C(=O)C1=O
InChI Key InChIKey=FQMSSTZJKSWSMP-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50009832
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against partially purified rat lens Aldose reductase at a dose of 5e-7MMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:In vitro inhibitory activity against rat kidney Aldehyde reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibitory activity measured against rat lens aldose reductase using 3-pyridinecarboxaldehyde as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with D-glucose as substratesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Percent inhibition of sorbitol accumulation in rat lens was measuredMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity was measured against renal inner medulla aldehyde reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of human placental aldose reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibitory activity was measured against renal outer medulla aldehyde reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with DL-glyceraldehyde as substratesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibitory activity was measured against pig kidney aldehyde reductase in the presence of 1 uM compound with 3-pyridine carboxaldehyde as substratesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with D-glucose as substratesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+5nMAssay Description:Inhibitory activity was measured against renal cortex aldehyde reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with D-glucose as substratesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity was measured against whole kidney aldehyde reductaseMore data for this Ligand-Target Pair