BDBM50009605 2-(pyridin-4-ylmethylene)-3,4-dihydronaphthalen-1(2H)-one::2-Pyridin-4-ylmethylene-3,4-dihydro-2H-naphthalen-1-one::2-[1-Pyridin-4-yl-meth-(E)-ylidene]-3,4-dihydro-2H-naphthalen-1-one::CHEMBL90585

SMILES O=C1\C(CCc2ccccc12)=C\c1ccncc1

InChI Key InChIKey=BMJBYWJCQGXHFI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50009605   

TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50009605(CHEMBL90585 | 2-(pyridin-4-ylmethylene)-3,4-dihydr...)
Affinity DataIC50: 9.30E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
UniversitäT De Saarlandes

Curated by ChEMBL
LigandPNGBDBM50009605(CHEMBL90585 | 2-(pyridin-4-ylmethylene)-3,4-dihydr...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against Steroidgenic Cytochrome P450 C18 using Bovine adrenal mitochondria.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50009605(CHEMBL90585 | 2-(pyridin-4-ylmethylene)-3,4-dihydr...)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibitory activity against Cytochrome P450 19A1 using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
UniversitäT De Saarlandes

Curated by ChEMBL
LigandPNGBDBM50009605(CHEMBL90585 | 2-(pyridin-4-ylmethylene)-3,4-dihydr...)
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibitory activity against Steroidgenic Cytochrome P450 17 alpha using rat testicular microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Rat)
American University of Ras Al Khaimah

Curated by ChEMBL
LigandPNGBDBM50009605(CHEMBL90585 | 2-(pyridin-4-ylmethylene)-3,4-dihydr...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of rat ovarian aromataseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed