BDBM50009505 2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-chloro-3H-imidazole-4-carboxylic acid::CHEMBL49170

SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=KYPAHCVBAFBKAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50009505   

TargetType-1 angiotensin II receptor(Bovine)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50009505(CHEMBL49170 | 2-Butyl-3-(2'-carboxy-biphenyl-4-ylm...)
Affinity DataIC50: 130nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor B(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50009505(CHEMBL49170 | 2-Butyl-3-(2'-carboxy-biphenyl-4-ylm...)
Affinity DataIC50: 92nMAssay Description:Binding affinity against angiotensin II receptor type 1 (AT1) from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Bovine)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50009505(CHEMBL49170 | 2-Butyl-3-(2'-carboxy-biphenyl-4-ylm...)
Affinity DataIC50: 130nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50009505(CHEMBL49170 | 2-Butyl-3-(2'-carboxy-biphenyl-4-ylm...)
Affinity DataIC50: 92nMAssay Description:Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2019
Entry Details Article
PubMed