BDBM50009307 DITOLYLGUANIDINE::Di-o-tolylguanidine

SMILES Cc1ccccc1NC(=N)Nc1ccccc1C

InChI Key InChIKey=OPNUROKCUBTKLF-UHFFFAOYSA-N

Data  71 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 72 hits for monomerid = 50009307   

TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKd:  18nMAssay Description:Binding affinity to sigma2 receptor in rat liver membranes incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Mouse)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]ifenprodil from GluN2B in mouse LTK cells assessed as inhibition constant measured after 120 mins by scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-(+)-pentazocine from recombinant human sigma1 receptor expressed in HEK293 cell membranes after 120 mins by microbeta scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  15nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  15nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-(+)-DTG from rat liver homogenate S2R incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  18nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in Sprague-Dawley rat liver membranes after 120 mins in presence of (+)-pentazocine by microbeta scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membrane assessed as inhibition constant incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in human RT4 cell membranes incubated for 120 mins in the presence of sigma1 receptor l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  28nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  28nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  37nMAssay Description:Displacement of [3H](+)-pentazocine from Sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in rat liver membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins measured for 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]-DTG from Sprague-Dawley rat liver sigma 2 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins in the presence of sigma1 receptor ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins in the presence of sigma1 receptor ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranes measured after 120 mins by solid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain membrane sigma 1 receptor assessed as inhibition constant measured after 120 mins by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes incubated for 120 mins measured for 5 mins by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-DTG from sigma 2 receptor in rat liver membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]di-O-tolylguanidine from sigma 2 receptor in rat liver membrane by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-DTG from sigma 2 receptor in rat liver membrane measured after 120 mins by microbeta counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi: >59nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in guinea pig brain homogenate after 120 mins by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor expressed in HEK293 cell membranes incubated for 120 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membrane incubated for 120 mins measured for 5 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor guinea pig brain membranes incubated for 150 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes after 120 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes measured after 120 mins by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
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