BDBM50009049 (+/-)(1-Methyl-2-phenyl-ethyl)-(4-phenyl-butyl)-amine; tosylate::(S)(1-Methyl-2-phenyl-ethyl)-(4-phenyl-butyl)-amine; tosylate::CHEMBL12047::US11999676, Compound 15

SMILES CC(Cc1ccccc1)NCCCCc1ccccc1

InChI Key InChIKey=LFAVXHNZCYGUPI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50009049   

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50009049(CHEMBL12047 | (+/-)(1-Methyl-2-phenyl-ethyl)-(4-ph...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50009049(CHEMBL12047 | (+/-)(1-Methyl-2-phenyl-ethyl)-(4-ph...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity towards sigma opioid receptor was determined in rat cerebral homogenate using [3H]haloperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50009049(CHEMBL12047 | (+/-)(1-Methyl-2-phenyl-ethyl)-(4-ph...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50009049(CHEMBL12047 | (+/-)(1-Methyl-2-phenyl-ethyl)-(4-ph...)
Affinity DataKi:  190nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent