BDBM50008997 1-Methyl-1,2-dihydro-indazol-3-one::CHEMBL412905

SMILES Cn1[nH]c(=O)c2ccccc12

InChI Key InChIKey=ONNIFDMRZCMQQM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008997   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008997(CHEMBL412905 | 1-Methyl-1,2-dihydro-indazol-3-one)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008997(CHEMBL412905 | 1-Methyl-1,2-dihydro-indazol-3-one)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008997(CHEMBL412905 | 1-Methyl-1,2-dihydro-indazol-3-one)
Affinity DataEC50: >6.74E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed