BDBM50008964 2,6-Di-tert-butyl-4-[2-(3-methyl-isoxazol-5-yl)-vinyl]-phenol::CHEMBL12302

SMILES Cc1cc(\C=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)on1

InChI Key InChIKey=DHCYTSABKOYFHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008964   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008964(CHEMBL12302 | 2,6-Di-tert-butyl-4-[2-(3-methyl-iso...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008964(CHEMBL12302 | 2,6-Di-tert-butyl-4-[2-(3-methyl-iso...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of 5-lipoxygenase measured by the reduction of leukotriene B4 (LTB4) in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008964(CHEMBL12302 | 2,6-Di-tert-butyl-4-[2-(3-methyl-iso...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against cyclooxygenase in rat basophilic leukemia cells using prostaglandin G/H synthase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed