BDBM50008287 2-{4-[2-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-yl)-1-methyl-ethyl]-benzoylamino}-pentanedioic acid::CHEMBL110251

SMILES CC(Cc1cnc2nc(N)nc(N)c2c1)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O

InChI Key InChIKey=IBBJCSZQBBGNDY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008287   

TargetDihydrofolate reductase(Mouse)
Sri International

Curated by ChEMBL
LigandPNGBDBM50008287(CHEMBL110251 | 2-{4-[2-(2,4-Diamino-pyrido[2,3-d]p...)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Sri International

Curated by ChEMBL
LigandPNGBDBM50008287(CHEMBL110251 | 2-{4-[2-(2,4-Diamino-pyrido[2,3-d]p...)
Affinity DataKi:  0.00700nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed