BDBM50007593 CHEMBL3238294

SMILES COc1cc(Cl)ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N

InChI Key InChIKey=VVOLULWSSXEMRK-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007593   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007593(CHEMBL3238294)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007593(CHEMBL3238294)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007593(CHEMBL3238294)
Affinity DataIC50: 366nMAssay Description:Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed