BDBM50007582 CHEMBL3238252

SMILES Cc1cc(c2nncn2n1)NCCc3ccc(cc3)O

InChI Key InChIKey=IRYZTIMDNVDWKI-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50007582   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human TNKS-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human TNKS-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 12nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 200nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed