BDBM50007465 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-butan-1-one::CHEMBL331603
SMILES [#6]-[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12
InChI Key InChIKey=DRBFNBBNYQHLBF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50007465
Affinity DataIC50: 3.30E+4nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
TargetSodium-dependent neutral amino acid transporter B(0)AT2(Human)
Max Planck Institute of Psychiatry
Curated by ChEMBL
Max Planck Institute of Psychiatry
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of eGFP-tagged human B0AT2 expressed in HEK293 cells measured within 10 mins by [3H]proline uptake assayMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 171nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in Sf9 cells by scintillation counting methodMore data for this Ligand-Target Pair