BDBM50007461 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-propan-1-one::CHEMBL116935

SMILES [#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12

InChI Key InChIKey=YRDLCPQSVCKVDA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007461   

TargetPlatelet-activating factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007461(CHEMBL116935 | 1-[4-(8-Chloro-5,6-dihydro-benzo[5,...)
Affinity DataIC50: 2.40E+3nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent neutral amino acid transporter B(0)AT2(Human)
Max Planck Institute of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50007461(CHEMBL116935 | 1-[4-(8-Chloro-5,6-dihydro-benzo[5,...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of eGFP-tagged human B0AT2 expressed in HEK293 cells measured within 10 mins by [3H]proline uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007461(CHEMBL116935 | 1-[4-(8-Chloro-5,6-dihydro-benzo[5,...)
Affinity DataKi:  48nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed