BDBM50007425 (S) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(S)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(S)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL330274

SMILES CCCN1CCc2cccc-3c2[C@@H]1Cc1ccc(O)c(O)c-31

InChI Key InChIKey=BTGAJCKRXPNBFI-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50007425   

TargetTyrosine 3-monooxygenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of tyrosine hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataIC50: 3.5nMAssay Description:Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]ADTN as the radioligand at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataIC50: 670nMAssay Description:Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]SPR as the radioligand at a concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataIC50: 5nMAssay Description:Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]APO as the radioligand at a concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataKi:  38nMAssay Description:Compound was evaluated for its ability to inhibit dopamine receptor D2 in rat striatum using [3H]-spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataKi:  370nMAssay Description:Compound was evaluated for its ability to inhibit Striatal Dopamine Receptor in rat brain through radioreceptor assay carried out with agonist ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50007425(CHEMBL330274 | (S)-6-propyl-5,6,6a,7-tetrahydro-4H...)
Affinity DataKi:  1.35E+3nMAssay Description:Compound was evaluated for its ability to inhibit Dopamine receptor D1 in rat striatum using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed