BDBM50007408 4-Phenyl-piperidine::4-phenylpiperidine::CHEMBL2011546::CHEMBL20969

SMILES C1CC(CCN1)c1ccccc1

InChI Key InChIKey=UTBULQCHEUWJNV-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50007408   

TargetVesicular acetylcholine transporter(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50007408(CHEMBL20969 | 4-phenylpiperidine | CHEMBL2011546 |...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM50007408(CHEMBL20969 | 4-phenylpiperidine | CHEMBL2011546 |...)
Affinity DataKi:  440nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007408(CHEMBL20969 | 4-phenylpiperidine | CHEMBL2011546 |...)
Affinity DataKi:  1.52E+3nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007408(CHEMBL20969 | 4-phenylpiperidine | CHEMBL2011546 |...)
Affinity DataKi:  1.98E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007408(CHEMBL20969 | 4-phenylpiperidine | CHEMBL2011546 |...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for the inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50007408(CHEMBL20969 | 4-phenylpiperidine | CHEMBL2011546 |...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-mesulergine from 5HT2C receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed