BDBM50007314 CHEMBL104834::[2-(3,4-Dichloro-phenyl)-ethyl]-(2-pyrrolidin-1-yl-cyclohexyl)-amine

SMILES Clc1ccc(CCN[C@@H]2CCCC[C@@H]2N2CCCC2)cc1Cl

InChI Key InChIKey=NREHOBGKKWFKES-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007314   

TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007314(CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...)
Affinity DataKi:  0.490nMAssay Description:Compound was tested for the inhibitory activity against Sigma opioid receptor by using [3H](+)-3-PPP as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007314(CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...)
Affinity DataKi:  6.88E+3nMAssay Description:Compound was tested for the inhibitory concentration against phencyclidine by using [3H]TCP as radioligand at PCP receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007314(CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...)
Affinity DataKi:  8.51E+3nMAssay Description:Compound was tested for the inhibitory concentration against dopamine receptor D2 by using [3H]()-sulpiride) as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed