BDBM50006990 CHEMBL299499::N-Adamantan-1-yl-N'-(4-iodo-phenyl)-guanidine

SMILES NC(Nc1ccc(I)cc1)=NC12CC3CC(CC(C3)C1)C2

InChI Key

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50006990   

TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataIC50: 491nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataEC50:  9.50E+3nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed